Title : Variable reactivity of an engineered cysteine at position 338 in cystic fibrosis transmembrane conductance regulator reflects different chemical states of the thiol.

Pub. Date : 2006 Mar 24

PMID : 16436375






1 Functional Relationships(s)
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1 The phenotype associated with the reactive, altered state could be replicated by exposing oocytes expressing T338C CFTR to CuCl2, but not by glutathionylation or nitrosylation of the thiol or by oxidation with hydrogen peroxide. cupric chloride CF transmembrane conductance regulator Homo sapiens