Title : Mercury toxicity in the shark (Squalus acanthias) rectal gland: apical CFTR chloride channels are inhibited by mercuric chloride.

Pub. Date : 2006 Mar 1

PMID : 16432888






1 Functional Relationships(s)
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1 When the shark rectal gland CFTR channel was expressed in Xenopus oocytes and chloride conductance was measured by two-electrode voltage clamping, we found that 1 microM HgCl2 inhibited forskolin/IBMX conductance by 69.2 +/- 2.0%. Colforsin cystic fibrosis transmembrane conductance regulator L homeolog Xenopus laevis