Title : Significance of the minor cytochrome P450 3A isoforms.

Pub. Date : 2006

PMID : 16430309






1 Functional Relationships(s)
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1 In the case of midazolam, ciclosporin, nifedipine and docetaxel, clearance by individuals with a CYP3A5-expressing genotype did not differ from that for nonexpressors, but in the case of tacrolimus, eight independent studies have demonstrated faster clearance by those carrying one or two CYP3A5*1 alleles. Cyclosporine cytochrome P450 family 3 subfamily A member 5 Homo sapiens