Title : A PKC-mediated backup mechanism of the MXXCW motif-linked switch for initiating tyrosine kinase activities.

Pub. Date : 2006 Feb 6

PMID : 16427628






1 Functional Relationships(s)
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1 We showed that all RET-PTC-1 mutants in which the C in this motif (C376) was replaced with glycine, lysine, threonine or serine lost their activity in vitro. Glycine ret proto-oncogene Homo sapiens