Pub. Date : 2006 Oct 28
PMID : 16427189
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, hypoxia activated the PI3K/Akt and ERK pathways, and blocking the activation of either pathway reversed resistance to UV- and etoposide-induced apoptosis in response to hypoxia. | Etoposide | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | These results suggest that hypoxia confers resistance to UV- or etoposide-mediated apoptosis in lung cancer cells via the activations of the PI3K/Akt and the ERK pathways. | Etoposide | AKT serine/threonine kinase 1 | Homo sapiens |