Title : Conjugated linoleic acid attenuates cyclooxygenase-2 transcriptional activity via an anti-AP-1 mechanism in MCF-7 breast cancer cells.

Pub. Date : 2006 Feb

PMID : 16424122






1 Functional Relationships(s)
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1 Using electrophoretic mobility shift assays, we found that the CLA mix reduced TPA-induced recruitment of nuclear proteins to a cAMP response element (CRE) in the COX-2 promoter and a consensus TPA-responsive element (TRE) in the collagenase-1 promoter. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens