Title : Laboratory and clinical studies of biochemical modulation by hydroxyurea.

Pub. Date : 1992 Jun

PMID : 1641659






1 Functional Relationships(s)
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1 High levels of deoxyuridine monophosphate that have been associated with resistance to 5-fluorouracil can be suppressed by hydroxyurea, leading to greater inhibition of thymidylate synthase. 2'-deoxyuridylic acid thymidylate synthetase Homo sapiens