Title : Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate.

Pub. Date : 2006 Mar

PMID : 16416302






1 Functional Relationships(s)
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1 CYP3A activity was determined from the measurement of testosterone 6beta-hydroxylation with human liver microsomes (HLM) and recombinant CYP3A4 as the enzyme sources. testosterone 6beta cytochrome P450 family 3 subfamily A member 4 Homo sapiens