Title : Reconstitution of chromatin transcription with purified components reveals a chromatin-specific repressive activity of p300.

Pub. Date : 2006 Feb

PMID : 16415879






1 Functional Relationships(s)
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1 We then examined the biochemical function of purified p300 in the absence of the endogenous factor and other related activities and found, unexpectedly, that p300 has a chromatin-specific, transcriptional repression activity that can be relieved by the addition of acetyl-CoA. Acetyl Coenzyme A E1A binding protein p300 Homo sapiens