Title : Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants.

Pub. Date : 2006 May 24

PMID : 16414224






1 Functional Relationships(s)
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1 Thirty samples of Indonesian medicinal plants were tested for their mechanism-based inhibition on cytochrome P450 3A4 (CYP3A4) and CYP2D6 via erythromycin N-demethylation and dextromethorphan O-demethylation activities in human liver microsomes. Erythromycin cytochrome P450 family 2 subfamily D member 6 Homo sapiens