Title : Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles.

Pub. Date : 2006 Feb

PMID : 16413574






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These data indicate that TNF inhibits endothelium-dependent NO-mediated dilation of coronary arterioles by ceramide-induced activation of JNK and subsequent production of superoxide via xanthine oxidase. Ceramides mitogen-activated protein kinase 8 Homo sapiens