Title : Different role for mouse and human CD3delta/epsilon heterodimer in preT cell receptor (preTCR) function: human CD3delta/epsilon heterodimer restores the defective preTCR function in CD3gamma- and CD3gammadelta-deficient mice.

Pub. Date : 2006 Apr

PMID : 16412509






1 Functional Relationships(s)
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1 To determine if human CD3delta/epsilon (hCD3delta/epsilon) could mediate preTCR-mediated DN to DP transition, we employed a human CD3 transgene that encodes full length CD3delta and a truncated but functional form of CD3epsilon. dn CD3 antigen, epsilon polypeptide Mus musculus