Title : A bromoenol lactone suicide substrate inactivates group VIA phospholipase A2 by generating a diffusible bromomethyl keto acid that alkylates cysteine thiols.

Pub. Date : 2006 Jan 24

PMID : 16411783






1 Functional Relationships(s)
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Protein Name
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1 Phospholipases A2 (PLA2) comprise a superfamily of enzymes that hydrolyze phospholipids to a free fatty acid, e.g., arachidonate, and a 2-lysophospholipid. Arachidonic Acid phospholipase A2 group VI Homo sapiens