Title : Thermic effect of epinephrine: a role for endogenous insulin.

Pub. Date : 1992 Jun

PMID : 1640844






3 Functional Relationships(s)
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1 The contribution of the basal insulin concentration to the metabolic response to epinephrine was measured in eight, postabsorptive, healthy volunteers before and during epinephrine (0.05 micrograms/kg fat-free mass [FFM] x min) and somatostatin (500 micrograms/h) infusion with and without insulin (0.1 mU/kg body weight [BW] x min) replacement. Epinephrine insulin Homo sapiens
2 At basal plasma insulin concentrations, epinephrine increased oxygen consumption, heart rate, heart work, hepatic glucose production, glycogen breakdown in liver and muscle, and glucose oxidation, and the arterial plasma concentrations of glucose, lactate, and free fatty acids. Epinephrine insulin Homo sapiens
3 We conclude that epinephrine-induced thermogenesis is partially inhibited by basal plasma insulin concentrations. Epinephrine insulin Homo sapiens