Title : N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells.

Pub. Date : 2006 May 4

PMID : 16407847






2 Functional Relationships(s)
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1 These data indicate that 4HPR-induced apoptosis is triggered by ROS increase, leading to the activation of the mitogen-activated protein serine/threonine kinases JNK, p38, PKC and ERK, and subsequent apoptosis. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens
2 These data indicate that 4HPR-induced apoptosis is triggered by ROS increase, leading to the activation of the mitogen-activated protein serine/threonine kinases JNK, p38, PKC and ERK, and subsequent apoptosis. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens