Title : Homotypic association between tumour-associated VHL proteins leads to the restoration of HIF pathway.

Pub. Date : 2006 May 18

PMID : 16407835






1 Functional Relationships(s)
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Protein Name
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1 A large number of disease-causing mutations in either the alpha or beta domain renders HIFalpha stable irrespective of oxygen tension, leading to the upregulation of numerous HIF-target genes, such as GLUT1 and VEGF. Oxygen solute carrier family 2 member 1 Homo sapiens