Pub. Date : 2006 Apr
PMID : 16407467
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, combined TauCl/5-ASA treatment additively inhibited TNF-dependent NF-kappaB activation. | Mesalamine | tumor necrosis factor | Homo sapiens |
2 | Together, our data suggest that the colon-specific carrier taurine contributes to the clinical effect of the prodrug by potentiating the inhibitory effect of the active ingredient 5-ASA on a major proinflammatory signal, TNF-dependent NF-kappaB activation in the inflamed large intestine. | Mesalamine | tumor necrosis factor | Homo sapiens |