Title : Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA.

Pub. Date : 2006 May 5

PMID : 16407196






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Overexpression of wild-type human Atrophin-1 could not rescue the motor and survival defects in Atro-118Q mice, indicating that the mutant protein with polyglutamine expansion does not simply function in a dominant negative manner. polyglutamine atrophin 1 Homo sapiens