Title : Concentration-dependent kinetics of acetylcholinesterase inhibition by the organophosphate paraoxon.

Pub. Date : 2006 Apr

PMID : 16403852






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1 However, more recently certain kinetic complexities in the inhibition of acetylcholinesterase by organophosphates such as paraoxon (O,O-diethyl O-(p-nitrophenyl) phosphate) and chlorpyrifos oxon (O,O-diethyl O-(3,5,6-trichloro-2-pyridyl) phosphate) have raised questions regarding the adequacy of the kinetic scheme on which k(i) is based. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens