Title : Decreased androgen receptor gene methylation in premature pubarche: a novel pathogenetic mechanism?

Pub. Date : 2006 Mar

PMID : 16403814






1 Functional Relationships(s)
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1 CONCLUSIONS: The increased AR gene activity observed in PP patients, as indicated by the reduced AR gene methylation pattern, together with the presence of shorter CAG repeats, might lead to hypersensitivity of the hair follicles to steroid hormones and therefore to the premature development of pubic hair. Steroids androgen receptor Homo sapiens