Title : Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet.

Pub. Date : 2006 Feb

PMID : 16397791






5 Functional Relationships(s)
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1 We tested whether the anti-diabetic effects of EPA and DHA involve enhanced production of the endogenous insulin sensitiser, adiponectin. Eicosapentaenoic Acid adiponectin, C1Q and collagen domain containing Mus musculus
2 EPA/DHA increased plasma adiponectin levels, independent of food intake, reflecting the stimulation of Adipoq expression in adipocytes and the release of adiponectin from WAT, particularly from epididymal fat. Eicosapentaenoic Acid adiponectin, C1Q and collagen domain containing Mus musculus
3 EPA/DHA increased plasma adiponectin levels, independent of food intake, reflecting the stimulation of Adipoq expression in adipocytes and the release of adiponectin from WAT, particularly from epididymal fat. Eicosapentaenoic Acid adiponectin, C1Q and collagen domain containing Mus musculus
4 EPA/DHA increased plasma adiponectin levels, independent of food intake, reflecting the stimulation of Adipoq expression in adipocytes and the release of adiponectin from WAT, particularly from epididymal fat. Eicosapentaenoic Acid adiponectin, C1Q and collagen domain containing Mus musculus
5 CONCLUSIONS/INTERPRETATION: Intake of diets rich in EPA and DHA leads to elevated systemic concentrations of adiponectin, largely independent of food intake or adiposity and explain, to some extent, their anti-diabetic effects. Eicosapentaenoic Acid adiponectin, C1Q and collagen domain containing Mus musculus