Title : Beta2-adrenergic receptor polymorphisms in African American children with status asthmaticus.

Pub. Date : 2006 Jan

PMID : 16395068






2 Functional Relationships(s)
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1 However, in children heterozygous for Glu at position 27 of the beta2-adrenergic receptor, the percentage of patients requiring aminophylline treatment, in addition to beta2-agonist therapy, was significantly higher than that seen in patients homozygous for Gln at that position (5/10 [50%] vs. 1/21 [5%], respectively; p = .002). Aminophylline adrenoceptor beta 2 Homo sapiens
2 CONCLUSIONS: African American children with status asthmaticus who have the Gln/Glu genotype at amino acid position 27 of the beta2-adrenergic receptor may benefit from aminophylline treatment in addition to beta2-agonist therapy. Aminophylline adrenoceptor beta 2 Homo sapiens