Title : The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members.

Pub. Date : 2006 Jan 15

PMID : 16393995






2 Functional Relationships(s)
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1 RFP inhibited activation of the IFN-stimulated response element and/or NF-kappaB mediated by the IKK family members and triggered by TNF, IL-1, polyinosinic-polycytidylic acid (ligand for TLR3), and viral infection. Poly I-C nuclear factor kappa B subunit 1 Homo sapiens
2 Moreover, knockdown of RFP expression by RNA interference-enhanced activation of IFN-stimulated response element and/or NF-kappaB triggered by polyinosinic-polycytidylic acid, TNF, and IL-1. Poly I-C nuclear factor kappa B subunit 1 Homo sapiens