Title : Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase.

Pub. Date : 2006 Jan 15

PMID : 16393992






1 Functional Relationships(s)
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1 IL-1beta and TNF-alpha rapidly stimulated the rate of hydrogen peroxide produced by isolated microglia, and this was inhibited by diphenylene iodonium, implying that the cytokines were acting directly on microglia to stimulate the NADPH oxidase. diphenyleneiodonium interleukin 1 beta Rattus norvegicus