Title : Metabolism and transport of oxazaphosphorines and the clinical implications.

Pub. Date : 2005

PMID : 16393888






1 Functional Relationships(s)
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1 The metabolism of oxazaphosphorines is auto-inducible, with the activation of the orphan nuclear receptor pregnane X receptor (PXR) being the major mechanism. oxazaphosphorines nuclear receptor subfamily 1 group I member 2 Homo sapiens