Title : Direct effects of neuroleptics on the activity of CYP2A in the liver of rats.

Pub. Date : 2005 Nov-Dec

PMID : 16382210






1 Functional Relationships(s)
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1 The obtained results show direct inhibitory effects of phenothiazine neuroleptics on the activity of CYP2A in rat liver, which may be of physiological importance for the metabolism of testosterone, considering simultaneous inhibition of CYP2C11 and CYP3A by those drugs. phenothiazine cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus