Pub. Date : 2006 Apr 1
PMID : 16374778
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PMA, which mimics diacylglycerol (DAG) as an activator of cPKC, novel-PKC (nPKC), and non-PKC DAG-driven molecule(s), produced a dose-dependent dual effect on phagocytosis by CR3/MAC-1 and SRAI/II, i.e., augmentation at low concentrations and inhibition at high concentrations. | Tetradecanoylphorbol Acetate | teratocarcinoma-derived growth factor 1 pseudogene 3 | Homo sapiens |
2 | Inhibition of phagocytosis by CR3/MAC-1 was enhanced by combining inhibiting concentrations of PMA with PKC inhibitors Go-6976 or Ro-318220, suggesting inhibition by PMA/DAG-driven non-PKC molecule(s). | Tetradecanoylphorbol Acetate | teratocarcinoma-derived growth factor 1 pseudogene 3 | Homo sapiens |