Title : A role for Ets1, synergizing with AP-1 and GATA-3 in the regulation of IL-5 transcription in mouse Th2 lymphocytes.

Pub. Date : 2006 Feb

PMID : 16373364






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 An important role for the proximal AP-1 and GATA sites in regulating IL-5 transcription is generally accepted but the significance of an adjacent Ets/NFAT site has remained unclear. gata interleukin 5 Mus musculus
2 Mutagenesis showed that the Ets/NFAT site is of critical importance along with the AP-1 and GATA sites in regulating IL-5 transcription stimulated by PMA/cAMP and MAP kinase activation. gata interleukin 5 Mus musculus