Title : Phosphodiesterase inhibition decreases nuclear factor-kappaB activation and shifts the cytokine response toward anti-inflammatory activity in acute endotoxemia.

Pub. Date : 2005 Sep

PMID : 16361898






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 IL-10 levels at 4 hours were up-regulated in both LPS and PTX + LPS-treated animals; however, levels were higher in the LPS groups, which paralleled high TNF-alpha levels. Pentoxifylline interleukin 10 Homo sapiens
2 In contrast, IL-10 levels at 4 and 24 hours in PTX + LPS-treated animals remained constant, whereas in LPS-treated animals, IL-10 levels at 24 hours were markedly decreased. Pentoxifylline interleukin 10 Homo sapiens