Title : Desensitization of 5-HT2A receptor function by chronic administration of selective serotonin reuptake inhibitors.

Pub. Date : 2006 Jan 5

PMID : 16360124






1 Functional Relationships(s)
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1 These results suggest that the desensitization of 5-HT2A receptor function occurs in the same way as that of 5-HT2C receptor function through chronic treatment with either fluvoxamine or paroxetine as a consequence of prolonged exposure to elevated levels of serotonin. Fluvoxamine 5-hydroxytryptamine receptor 2C Rattus norvegicus