Title : Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis.

Pub. Date : 2005 Dec 15

PMID : 16357177






2 Functional Relationships(s)
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1 Here, we show that bortezomib promotes apoptosis triggered by classic ER stress inducers (tunicamycin and thapsigargin) via a c-Jun NH(2)-terminal kinase (JNK)-dependent mechanism. Tunicamycin mitogen-activated protein kinase 8 Homo sapiens
2 Here, we show that bortezomib promotes apoptosis triggered by classic ER stress inducers (tunicamycin and thapsigargin) via a c-Jun NH(2)-terminal kinase (JNK)-dependent mechanism. Tunicamycin mitogen-activated protein kinase 8 Homo sapiens