Pub. Date : 2005 Dec 15
PMID : 16357151
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hydrogen peroxide was produced as a by-product of LOX activity and the removal of hydrogen peroxide by catalase treatment in invasive breast cancer cells led to a dose-dependent loss in Src activation. | Hydrogen Peroxide | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
2 | Hydrogen peroxide was produced as a by-product of LOX activity and the removal of hydrogen peroxide by catalase treatment in invasive breast cancer cells led to a dose-dependent loss in Src activation. | Hydrogen Peroxide | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
3 | These results suggest that LOX facilitates migration and cell-matrix adhesion formation in invasive breast cancer cells through a hydrogen peroxide-mediated mechanism involving the FAK/Src signaling pathway. | Hydrogen Peroxide | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |