Title : Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage.

Pub. Date : 2006 Jan

PMID : 16354677






1 Functional Relationships(s)
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1 Treatment with EX-527 dramatically increased acetylation at lysine 382 of p53 after different types of DNA damage in primary human mammary epithelial cells and several cell lines. Lysine tumor protein p53 Homo sapiens