Title : Steroidogenic factor 1 gene transcription is inhibited by transforming growth factor beta.

Pub. Date : 2005

PMID : 16353668






1 Functional Relationships(s)
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1 We conclude that in Y-1 cells TGF-beta inhibits the expression of SF-1 gene at a transcriptional level, and we postulate that the inhibitory effect of TGF-beta on steroid hormone synthesis in the adrenal cortex could be due to an attenuated transcription of Sf-1. Steroids transforming growth factor beta 1 Homo sapiens