Title : Significance of COX-2 expression in human esophageal squamous cell carcinoma.

Pub. Date : 2006 Jun

PMID : 16352617






1 Functional Relationships(s)
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1 Further, treatment of human ESCC cell lines (KYSE450 and KYSE510) with NS-398, a COX-2 specific chemical inhibitor, suppressed the production of prostaglandin E2 (PGE2) and induced cell growth inhibition, cell cycle arrest at the G1-S checkpoint, and the expression of cyclin-dependent kinase inhibitors p21waf1/cip1 and p27kip1. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide cyclin dependent kinase inhibitor 1B Homo sapiens