Title : Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8.

Pub. Date : 2006 Feb 17

PMID : 16352607






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The ATP-binding cassette half-transporters ABCG5 (G5) and ABCG8 (G8) promote secretion of neutral sterols into bile, a major pathway for elimination of sterols. Sterols ATP binding cassette subfamily G member 5 Mus musculus
2 The ATP-binding cassette half-transporters ABCG5 (G5) and ABCG8 (G8) promote secretion of neutral sterols into bile, a major pathway for elimination of sterols. Sterols ATP binding cassette subfamily G member 5 Mus musculus
3 Mutations in either ABCG5 or ABCG8 cause sitosterolemia, a recessive disorder characterized by impaired biliary and intestinal sterol secretion, sterol accumulation, and premature atherosclerosis. Sterols ATP binding cassette subfamily G member 5 Mus musculus
4 Mutations in either ABCG5 or ABCG8 cause sitosterolemia, a recessive disorder characterized by impaired biliary and intestinal sterol secretion, sterol accumulation, and premature atherosclerosis. Sterols ATP binding cassette subfamily G member 5 Mus musculus