Title : Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation.

Pub. Date : 2006 Feb

PMID : 16341234






1 Functional Relationships(s)
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1 We also show that BzATP and ATP activate ERK1/2 by two different pathways since ERK1/2 activation by BzATP, but not by ATP, is blocked by the tryrosine kinase inhibitor, genistein, and the Src protein kinase inhibitor, tyrphostin. Tyrphostins SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens