Pub. Date : 2005 Dec
PMID : 16339749
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Levodopa reportedly inhibits insulin action in skeletal muscle. | Levodopa | insulin | Homo sapiens |
| 2 | Here we show that C2C12 myotubes produce levodopa and that insulin-stimulated glucose transport is enhanced when endogenous levodopa is depleted. | Levodopa | insulin | Homo sapiens |
| 3 | Exogenous levodopa prevented the stimulation of glucose transport by insulin (P < 0.05) and increased cAMP concentrations (P < 0.05). | Levodopa | insulin | Homo sapiens |
| 4 | The decrease in insulin-stimulated glucose transport caused by levodopa was attenuated by propranolol (a beta-adrenergic antagonist) and prevented by NSD-1015 (NSD), an inhibitor of DOPA decarboxylase (DDC; converts levodopa to dopamine). | Levodopa | insulin | Homo sapiens |
| 5 | The decrease in insulin-stimulated glucose transport caused by levodopa was attenuated by propranolol (a beta-adrenergic antagonist) and prevented by NSD-1015 (NSD), an inhibitor of DOPA decarboxylase (DDC; converts levodopa to dopamine). | Levodopa | insulin | Homo sapiens |