Pub. Date : 2006 Feb 10
PMID : 16338928
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Selective activation of PKC by 12-O-tetradecanoylphorbol-13-acetate (TPA) reduced phospho-Ser-473-Akt, suggesting that activation of PKC inhibits Akt activity. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Selective activation of PKC by 12-O-tetradecanoylphorbol-13-acetate (TPA) reduced phospho-Ser-473-Akt, suggesting that activation of PKC inhibits Akt activity. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | Selective activation of PKC by 12-O-tetradecanoylphorbol-13-acetate (TPA) reduced phospho-Ser-473-Akt, suggesting that activation of PKC inhibits Akt activity. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 4 | Selective activation of PKC by 12-O-tetradecanoylphorbol-13-acetate (TPA) reduced phospho-Ser-473-Akt, suggesting that activation of PKC inhibits Akt activity. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 5 | TPA also attenuated IGF-1 and epidermal growth factor-induced phospho-Ser-473-Akt, reduced Akt kinase activity, and blocked IGF-1 protection from UVC-induced apoptosis. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 6 | TPA also attenuated IGF-1 and epidermal growth factor-induced phospho-Ser-473-Akt, reduced Akt kinase activity, and blocked IGF-1 protection from UVC-induced apoptosis. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 7 | The inhibition of Akt activity by TPA was reduced by inhibitors of protein phosphatase 2A, and TPA stimulated the association of phosphatase 2A with Akt. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 8 | The inhibition of Akt activity by TPA was reduced by inhibitors of protein phosphatase 2A, and TPA stimulated the association of phosphatase 2A with Akt. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 9 | The inhibition of Akt activity by TPA was reduced by inhibitors of protein phosphatase 2A, and TPA stimulated the association of phosphatase 2A with Akt. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |