Title : Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors.

Pub. Date : 2006 Mar 1

PMID : 16332437






1 Functional Relationships(s)
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1 anti-Substituted beta-methylphenylalanine derived amides have been shown to be potent DPP-IV inhibitors exhibiting excellent selectivity over both DPP8 and DPP9. Amides dipeptidyl peptidase 4 Homo sapiens