Pub. Date : 2005 Dec
PMID : 16332238
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of cyclosporin A on the expression of inducible nitric oxide synthase in the gingiva of rats. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
| 2 | Significantly greater iNOS enzyme activities were detected in lung and gingival tissues obtained from CsA-treated animals than from control animals. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
| 3 | In addition, cells positively staining for iNOS were clearly observed in both gingival and lung tissues obtained from the CsA-treated animals by immunohistochemistry, whereas a few stained cells were found in those from the control group. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
| 4 | CONCLUSIONS: The effect of CsA on gingival iNOS expression was evaluated in rats for 4 weeks. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
| 5 | A greater iNOS expression in the gingiva was observed after CsA therapy by both enzyme activities and immunohistochemica staining. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
| 6 | Therefore, we suggest that CsA can increase gingival iNOS expression, which may play an important role in cyclosporin-induced gingival overgrowth. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |
| 7 | Therefore, we suggest that CsA can increase gingival iNOS expression, which may play an important role in cyclosporin-induced gingival overgrowth. | Cyclosporine | nitric oxide synthase 2 | Rattus norvegicus |