Title : Predominant T helper type 2-inflammatory responses promote murine colon cancers.

Pub. Date : 2006 May 1

PMID : 16331625






2 Functional Relationships(s)
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1 When IFN-gamma(-/-) mice were treated with AOM and TNBS, significantly higher number of tumors were seen (8.4 +/- 1.7) than in WT (3.3 +/- 2.9) or IL-4(-/-) (3.1 +/- 3.4) mice, which received identical treatments. Trinitrobenzenesulfonic Acid interleukin 4 Mus musculus
2 A separate set of experiment, using less doses of AOM and TNBS also showed the higher frequency of tumor formation in IFN-gamma(-/-) mice than in IL-4(-/-) mice. Trinitrobenzenesulfonic Acid interleukin 4 Mus musculus