Title : Opposing actions of angiotensin II type 1 and 2 receptors on plasma cholesterol levels in rats.

Pub. Date : 2006 Jan

PMID : 16331107






2 Functional Relationships(s)
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1 In the AII-infused rats treated with olmesartan medoxomil, an AT1R blocker, we were interested to observe significant decreases in plasma TC and non-high-density lipoprotein (HDL)-cholesterol (C) (TC minus HDL-C), and liver cholesterol content were also decreased. olmesartan angiotensinogen Rattus norvegicus
2 The AII infusion led to significant elevations in TC and non-HDL-C in the fructose-fed rats, and olmesartan treatment completely rectified this AII-induced hypercholesterolemia. olmesartan angiotensinogen Rattus norvegicus