Pub. Date : 2006 Feb 15
PMID : 16330141
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation. | Azoles | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |
| 2 | Inhibition of CYP19 (aromatase) is the working principle for tumor therapy, but is an unwanted side effect of azoles used as fungicides or antifungal drugs. | Azoles | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |
| 3 | The inhibition of recombinant human CYP19 by 21 azoles in use for the three different purposes was investigated using the natural substrate testosterone. | Azoles | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |