Pub. Date : 2005 Nov
PMID : 16321618
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to evaluate the effect of itraconazole, a CYP3A inhibitor, on the plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients in relation to CYP2D6 genotype. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | In addition, the active moiety (risperidone plus 9-hydroxyrisperidone) also increased similarly, by 71% (P < .001) and 73% (P < .05), respectively, with itraconazole, without a significant difference between CYP2D6 genotypes. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |