Title : Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages.

Pub. Date : 2006 Sep

PMID : 16321392






1 Functional Relationships(s)
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1 First, we have shown by ELISA that 1 microM simvastatin significantly reduced MCP-1 in endothelial cells (ECs) and macrophages stimulated with TNF-alpha or IFN-gamma, respectively. Simvastatin tumor necrosis factor Mus musculus