Title : Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages.

Pub. Date : 2006 Sep

PMID : 16321392






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Messenger RNA analysis revealed that expression of the chemokines MCP-1, MIP-1alpha and MIP-1beta, as well as the chemokine receptors CCR1, CCR2, CCR4 and CCR5, was decreased by simvastatin, both in ECs and macrophages. Simvastatin C-C motif chemokine ligand 3 Homo sapiens