Title : Proteasome impairment does not contribute to pathogenesis in R6/2 Huntington's disease mice: exclusion of proteasome activator REGgamma as a therapeutic target.

Pub. Date : 2006 Jan 1

PMID : 16311253






1 Functional Relationships(s)
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1 Capping of proteasomes with REGgamma could therefore contribute to a potential "clogging" of the proteasome by pathogenic polyglutamines. polyglutamine proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) Mus musculus