Title : The induction of heme oxygenase 1 decreases contractility in human internal thoracic artery and radial artery grafts.

Pub. Date : 2005 Dec

PMID : 16308001






4 Functional Relationships(s)
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1 The aim of our study was to induce heme oxygenase 1 by using hemin in human internal thoracic and radial arteries and to evaluate the effect of this induction on the contractility of these arterial grafts. Hemin heme oxygenase 1 Homo sapiens
2 Immunohistochemical staining revealed a large expression of heme oxygenase 1 in all vascular layers of hemin-treated internal thoracic artery and radial artery rings. Hemin heme oxygenase 1 Homo sapiens
3 Enzyme-linked immunosorbent assay studies showed a significant increase in heme oxygenase 1 levels in hemin-treated internal thoracic artery and radial artery rings. Hemin heme oxygenase 1 Homo sapiens
4 CONCLUSION: Hemin caused in vitro induction of heme oxygenase 1 in human internal thoracic artery and radial artery grafts. Hemin heme oxygenase 1 Homo sapiens