Title : Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter.

Pub. Date : 2005 Dec 1

PMID : 16302792






2 Functional Relationships(s)
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1 Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter. Rhodamines solute carrier family 6 member 3 Homo sapiens
2 The resulting 2-substituted (5) and N-substituted (9) rhodamine-labeled ligands provided the highest DAT binding affinities expressed in COS-7 cells (Ki= 27 and 18 nM, respectively) in the series. Rhodamines solute carrier family 6 member 3 Homo sapiens